Roundtrip Flights from Des Moines, IA (DSM) to Milan, Italy (MXP) $529 (Travel late-Oct to early-Dec, 2025)

United Airlines and Expedia have round trip airfares travelling from Des Moines IA (DSM) to Milan Italy (MXP) for $529. These are basic economy fares that only allow a personal item and a carry-on bag. Travel availability: Departs DSM: Oct 27-31; Nov 4-7, 9-18, 25; Dec 2-3, Returns: Nov 3-27; Dec 2, 9-11, 16-17